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25/Jun/2021

Traumatic brain injury is damage to the brain that is the result of a head injury. Quality of life is greatly diminished for those living with a traumatic brain injury. Even fatal results can occur. As the quantity of study devoted to CBD develops, there is the rise in the query that whether CBD can help in treating brain injury or not. Currently, the research indicates that CBD possesses neuroprotective properties. Such effects can include mitigating the effect of head injuries.

A flexible and effective anti-inflammatory cannabinoid that has few to no adverse effects is known as cannabidiol or CBD. The number of conditions treatable with CBD increases daily with the introduction of fresh scientific information. There is emerging evidence that CBD is starting to be used as a treatment for severe traumatic brain injury.

TBI can happen to anyone who suffers from brain trauma, and it can affect every aspect of life.

What Do We Understand from Traumatic Brain Injury?

Any brain injury merits serious concern. The brain goes through a cascade of reactions after sustaining a significant injury. Inflammation, edema, and immunological activation are included in this list.

Though this is a usual and helpful set of reflexes in response to a break or fracture. Additional neurological damage might result from this set of events. 

When brain cells die, the damage to the brain as a whole will soon follow. Common TBI patients include people who have served in the military, professional athletes, and victims of motor vehicle collisions. TBI can have enduring and crippling repercussions, and might manifest emotionally, physically, behaviorally, and socially.

A lot of the time, these impacts are life-altering. As well as cognitive deterioration and impaired motor function, depression and anxiety are common side effects. Severe symptoms among certain people with TBI can also result in seizures. Conventional medicine currently lacks effective treatments for minor TBI, which is an underreported and frequently misdiagnosed condition.

Scientific Evidence Which Says CBD is Effective for TBI

CBD is showing some evidence of usefulness in reducing some of the harmful effects of TBI, specifically in the areas of inflammation and neurological complications.

A paper published in Frontiers in Pharmacology claims that “The Endocannabinoid System Possesses Potentially Drugable Receptor and Enzyme Targets for the Treatment of Varying TBI Pathology.”

In addition, there are numerous studies which suggest that in combination with THC, CBD is neuroprotective, indicating that regular ingestion of cannabinoids reduces the likelihood of a catastrophic brain injury.

More and more research about TBI is becoming available with each passing year. A variety of research studies agree that the ECS plays a major role in the development of mental, bodily, and behavioral responses after a TBI. 

Although further study is needed to produce precise protocols that may be accessible and recommended by mainstream medicine, some preliminary research has already been done. Each example is adding information to the outlook for the condition treated with cannabinoids.

Anecdotal Support for Using CBD as a Treatment for Brain Injury

It takes years for new scientific information to be studied and released. To draw a conclusion, you first must subject the drug being investigated, in this case CBD, to rigorous testing.

While scientific studies take time, evidence exists for the benefits of cannabis in treating brain injury based on anecdotes from patients.

CBD has the potential to improve the quality of life for people who have suffered a brain injury by allowing them to increase their quality of life. 

Final Words

CBD’s brain-healing qualities are not yet fully understood and must be investigated further. Much research is being conducted regularly, and soon we will get a clearer understanding of the role of CBD in TBI. The current research suggests that CBD has some properties which can help increase quality of life in brain injury, but we cannot be sure how effective it is or if it has any side effects. We have to wait for more research to be conducted and results to be announced; only then can we be sure about how effective it is to use CBD as a treatment for brain injury. 

About the author:

Sean Roberts is a writer by profession. He is a full time writer working with NY Marijuana Card, a leading clinic that provides medical marijuana recommendations. He aims at educating people about the medicinal use of cannabis https://nymarijuanacard.com/


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30/Oct/2019

“Let food be thy medicine, and let medicine be thy food”; a famous quote from the Classical Grecian physician Hippocrates. Lions Mane mushrooms are a perfect embodiment of this philosophy; as delicious as it is therapeutic. 

Lions mane (Hericium Erinaceus) is a white clumpy mushroom with long dangling spines that tends to grow in late summer/early fall on hardwoods.

I was first introduced to Lion’s Mane a few years ago when I had a few patients tell me they were using an extract of the mushroom to help with memory. Supplements that enhance brain activity, AKA Nootropics, have always tweaked my interest as one of my areas of clinical focus is in neurology. At first I thought that maybe this is the newest “superfood fad” but once I began to investigate the research on this mushroom my opinion quickly changed.

It was clear that Lions Mane had some legitimate therapeutic value in inflammation, the immune system, psychiatric conditions, cognitive enhancement, diabetes, heart disease, bowel disease and cancer.

Lions Mane Mushroom
Preparing Lions Mane Mushroom in my kitchen

Inflammation and Depression

A 2012 study demonstrated that Lions Mane mushroom contains several compounds that have moderate to high levels of antioxidant capacity. This translates into an anti-inflammatory effect in the body. A 2015 study demonstrated that participants who consumed Lions Mane had less depressive symptoms and improvements in blo-markers of depression which was attributed to it’s anti-inflammatory effects.  Another study demonstrated that Lions Mane can enhance immune function possibly by reducing inflammation and oxidative stress. 

Immune 

Not only does Lions Mane help boost immune function by reducing oxidative stress, it also seems to benefit intestinal immune function. A study on mice revealed that some of the proteins in the mushroom help encourage the growth of beneficial bacteria in the gut. 

Naturopathic Treatment for Multiple Sclerosis

Memory

Cognitive enhancement is the main reason that I see people taking this mushroom. It is possible that it does have some cognitive enhancement properties but all the research so far has been done on animals. One such study found that mice given a lion’s mane supplement had better object recognition and recognition memory. Other research suggests that Lions Mane may have the potential to prevent or treat conditions of cognitive decline like Alzheimer’s and Parkinson’s disease.

Heart Health

Heart Health

Research on rats has demonstrated that Lions Mane may have cholesterol lowering effects and blood pressure lowering effects. Compounds in Lions Mane may help in the production of Nitric Oxide, which helps keep blood vessels relaxed. 

Cancer

The antioxidant properties of Lions Mane may contribute to some anti-cancer effects seen in rat and in vitro studies. One in vitro study indicated that Lions Mane has activity against human leukemia cells. Another study showed that in mice, Lions Mane has activity against Liver, Colon and Gastric cancer cells. 

Diabetes

After 4 weeks of Lions Mane supplementation, rats with diabetes had lower blood sugar levels than those who did not receive the mushroom.  Diabetes can often result in life altering nerve damage. A 2015 study showed that diabetic rats given an extract of Lions Mane had reduced nerve pain and improved antioxidant activity after 6 weeks. 

Intestinal Health

Digestive Health

I previously discussed how Lions mane can have anti-inflammatory effect of the digestive tract, as well as benefitting the growth of “good” intestinal bacteria. Another study demonstrated that Lions Mane has some interesting antimicrobial effects. Notably, Lions Mane seems to inhibit the growth of H-pylori, a bacteria responsible for close to 80% of stomach ulcers.

Nerve Repair

One of the most fascinating health benefits of Lions Mane came out of a rat study. Rats with nerve damage who were given daily extracts of Lions mane had quicker nerve cell regeneration than those who did not. 

Culinary 

Up until a few weeks ago I thought Lions Mane was an exotic mushroom that was only used therapeutically as a supplement.  Recently, I found myself in a local Farmers Market and low and behold a mushroom farmer was selling fresh Lions Mane; I was amazed! I asked the farmer “how do I prepare this”? He told me to cut the mushroom in ½ inch slices and in a hot pan with butter, sear both sides. So, I bought some and followed his advice, and discovered that Lions Mane is absolutely delicious! It is now one of my favorite cooking mushrooms and I have since heard from many foodies and chefs that it is one of their favorites too. So let food be thy medicine everyone, and cook up some Lions Mane this fall!

Citations


Leonard, Jayne. “What are the benefits of lion’s mane mushrooms?.” Medical News Today. MediLexicon, Intl., 22 Oct. 2018. Web.
30 Oct. 2019. <https://www.medicalnewstoday.com/articles/323400.php>


Leonard, J. (2018, October 22). “What are the benefits of lion’s mane mushrooms?.” Medical News Today. Retrieved from
https://www.medicalnewstoday.com/articles/323400.php.

Lion’s Mane Mushroom, <i>Hericium erinaceus</i> (Bull.: Fr.) Pers. Suppresses H<sub>2</sub>O<sub>2</sub>-Induced Oxidative Damage and LPS-Induced Inflammation in HT22 Hippocampal Neurons and BV2 Microglia.
Kushairi N, Phan CW, Sabaratnam V, David P, Naidu M.
Antioxidants (Basel). 2019 Aug 1;8(8). pii: E261. doi: 10.3390/antiox8080261.
PMID: 31374912 [PubMed] Free Article
Thirteen-Week Oral Toxicity Evaluation of Erinacine AEnriched Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), Mycelia in Sprague-Dawley Rats.
Lee LY, Li IC, Chen WP, Tsai YT, Chen CC, Tung KC.
Int J Med Mushrooms. 2019;21(4):401-411. doi: 10.1615/IntJMedMushrooms.2019030320.
PMID: 31002635 [PubMed – indexed for MEDLINE]
In Vitro and In Vivo Inhibition of Helicobacter pylori by Ethanolic Extracts of Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes).
Wang G, Zhang X, Maier SE, Zhang L, Maier RJ.
Int J Med Mushrooms. 2019;21(1):1-11. doi: 10.1615/IntJMedMushrooms.2018029487.
PMID: 30806251 [PubMed – indexed for MEDLINE]
Dietary Supplementation of Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), and Spatial Memory in Wild-Type Mice.
Rossi P, Cesaroni V, Brandalise F, Occhinegro A, Ratto D, Perrucci F, Lanaia V, Girometta C, Orrù G, Savino E.
Int J Med Mushrooms. 2018;20(5):485-494. doi: 10.1615/IntJMedMushrooms.2018026241.
PMID: 29953363 [PubMed – indexed for MEDLINE]
A Polysaccharide Isolated from Mycelia of the Lion’s Mane Medicinal Mushroom Hericium erinaceus (Agaricomycetes) Induced Apoptosis in Precancerous Human Gastric Cells.
Wang M, Zhang Y, Xiao X, Xu D, Gao Y, Gao Q.
Int J Med Mushrooms. 2017;19(12):1053-1060. doi: 10.1615/IntJMedMushrooms.2017024975.
PMID: 29431066 [PubMed – indexed for MEDLINE]
Anti-Inflammatory Effects of Ethanol Extract of Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), in Mice with Ulcerative Colitis.
Qin M, Geng Y, Lu Z, Xu H, Shi JS, Xu X, Xu ZH.
Int J Med Mushrooms. 2016;18(3):227-34. doi: 10.1615/IntJMedMushrooms.v18.i3.50.
PMID: 27481156 [PubMed – indexed for MEDLINE]

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Patient focused integrative health care. Utilizing effective natural approaches designed to be used alone or to compliment conventional medical care.


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