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02/Oct/2023

Aging is an inevitable part of life, but modern science is continually uncovering ways to potentially slow down this process. This blog aims to provide an overview of the aging process and highlight some scientifically-backed strategies for slowing it down.

Understanding the Aging Process

The aging process is complex and influenced by a variety of factors. As we age, our bodies undergo numerous changes at the molecular, cellular, and organ levels that can lead to increased vulnerability to disease and death. Oxidative stress, inflammation, and cellular damage are key contributors to this process.

For instance, oxidative stress caused by free radicals contributes to the aging process and is associated with several age-related diseases. Inflammation, both chronic and acute, has been linked to aging and age-related diseases. Moreover, cellular damage and the inability of cells to repair this damage is another significant factor in aging.

Anti-Aging Strategies: Supplements, Diets, and Treatments

Vitamin D

Supplements

Here, we will explore some of the most potent anti-aging mechanisms and how they work.

Antioxidants

Antioxidants help neutralize free radicals, reducing oxidative stress and slowing down the aging process. A recent study indicates that antioxidant supplementation can improve skin health and slow the progression of age-related diseases.

  1. Vitamin C: This potent antioxidant boosts the immune system and aids in collagen production. Citrus fruits like oranges, lemons, and grapefruits, as well as strawberries, bell peppers, and broccoli, are excellent sources of Vitamin C. Try a refreshing citrus salad or squeeze some lemon juice into your water for a Vitamin C boost.
  2. Vitamin E: Vitamin E protects cell membranes and enhances skin health. You can find it in foods like almonds, spinach, sweet potatoes, and avocados. Enjoy a handful of almonds as a snack or whip up a creamy avocado smoothie.
  3. Beta-Carotene: This antioxidant converts into vitamin A in the body, promoting eye health and supporting the immune system. Carrots, sweet potatoes, and dark leafy greens like spinach and kale are rich in beta-carotene. Toss these veggies into a colourful salad or blend them into a nutrient-packed green smoothie.
  4. Selenium: Selenium is essential for reproduction, thyroid hormone metabolism, and DNA synthesis. It’s found in Brazil nuts, seafood, and whole grains. Try a selenium-rich snack like a handful of Brazil nuts or a whole grain toast.
  5. Flavonoids: These are powerful antioxidants found in a variety of fruits and vegetables, as well as tea and chocolate. Berries, apples, onions, and dark chocolate are all high in flavonoids. Whip up a berry smoothie bowl for breakfast or indulge in a piece of dark chocolate for dessert.

Coenzyme Q10 (CoQ10)

CoQ10 is a powerful antioxidant that plays a critical role in energy production within our cells. As we age, our natural levels of CoQ10 diminish, making supplementation beneficial. Recent research suggests that CoQ10 can improve heart health and cognitive function in older adults.

Resveratrol

Resveratrol, a compound found in red wine and dark chocolate, activates certain genes called sirtuins, which have been linked to longevity. A recent study showed that resveratrol supplementation could improve health and lifespan in mice.

Omega-3 Fatty Acids

Omega-3 fatty acids, found abundantly in fish oil, have potent anti-inflammatory effects and can help protect against age-related cognitive decline. A recent study suggested that omega-3 supplements might slow biological aging by prolonging telomere length.

NMN

NMN (Nicotinamide Mononucleotide) is a precursor to NAD+, a compound that plays a crucial role in energy metabolism and maintaining proper cell function. Recent research suggests that NMN supplementation can enhance longevity and improve various aspects of health.

Hormone Replacement Therapy (HRT)

HRT can help balance hormone levels that naturally decline with age, such as estrogen and testosterone. This can lead to improved energy, mood, and overall well-being. However, HRT should be used under professional supervision due to potential side effects and risks.

For more on hormone replacement Click Here

Adaptogens

Adaptogens are natural substances that help the body adapt to stress and promote balance. They include herbs like ashwagandha, rhodiola, and ginseng. Some studies suggest that adaptogens can improve mental performance, reduce fatigue, and boost immune health.

Diets

Dietary habits play a significant role in the aging process. Diets rich in fruits, vegetables, lean proteins, and whole grains have been associated with longer lifespans and reduced risk of chronic diseases.

The Mediterranean Diet

The Mediterranean diet, rich in fruits, vegetables, whole grains, lean proteins, and healthy fats, has been associated with longer lifespans and reduced risk of chronic diseases. This diet is high in antioxidants which neutralize harmful free radicals, reducing oxidative stress and slowing down aging.

Evidence from the Predimed study, a large, long-term nutritional intervention study, showed that adherence to the Mediterranean diet improved heart health and cognitive function and reduced the risk of cancer and mortality.

The Okinawa Diet

The Okinawa diet, based on the traditional dietary habits of Okinawa islanders in Japan, is another diet linked to longevity. This diet is low in calories but high in nutrients, consisting mainly of sweet potatoes, soy products, and a plethora of fruits and vegetables.

The Okinawa diet is high in antioxidants and flavonoids, which protect against oxidative stress and inflammation. A study on Okinawa islanders found that this diet contributed to their long lifespan and low rates of age-related diseases.

The Blue Zones Diet

The Blue Zones diet is inspired by the dietary habits of people living in the Blue Zones, five regions worldwide known for their high concentration of centenarians. This diet emphasizes plant-based foods, whole grains, and legumes, with meat and processed foods consumed sparingly.

Research shows that the Blue Zones diet can reduce the risk of chronic diseases and promote longevity. This is largely attributed to its high content of antioxidants, fibre, and healthy fats.

Caloric Restriction

Caloric restriction (CR) is a dietary regimen that involves reducing daily calorie intake without malnutrition or deprivation of essential nutrients.

A wealth of research has shown that CR can effectively slow down the aging process and confer a host of other health benefits. At the cellular level, CR works by reducing metabolic rate and oxidative stress, both of which are key contributors to aging. In addition, CR enhances insulin sensitivity, which can help prevent age-related diseases like diabetes. However, it’s important to note that CR should be undertaken with caution and under the guidance of a health professional, as drastic calorie reduction can lead to nutritional deficiencies and other health issues.

For more on caloric restriction Click Here

Stretching

Lifestyle/Therapies

Exercise

Regular exercise is a powerful tool for maintaining vitality; it boosts cardiovascular health, improves muscle tone, and enhances cognitive function.

Exercise, often hailed as the fountain of youth, plays a pivotal role in slowing down the natural aging process. Regular physical activity, regardless of the type, boosts overall well-being, preventing age-related diseases and promoting cellular regeneration. For instance, endurance exercises like walking, swimming, or cycling can significantly improve cardiovascular health and enhance longevity. Strength training, on the other hand, helps in maintaining muscle mass, which naturally tends to decline with age.

Furthermore, exercise has a profound effect on our tendons, which adapt to aging and physical activity. Exercise promotes their strength and flexibility, contributing to improved mobility and a reduced risk of injury. Besides, dance-based training, which is both fun and effective, can significantly improve balance in adults and older individuals.

Including a regular exercise routine doesn’t have to be overwhelming. It could be as simple as a 30-minute brisk walk daily, practicing yoga, or even dancing to your favourite tunes. The key is consistency and making exercise an enjoyable part of your lifestyle. Remember, staying physically active is not just about adding years to life, but life to years.

For more on exercise Click Here

Acupuncture

Acupuncture, a cornerstone of traditional Chinese medicine, offers a natural, holistic approach to slow down the aging process. This ancient therapy involves the careful insertion of fine needles into specific pressure points on the body by a qualified acupuncturist. It’s more than just a simple needle play; it’s a well-coordinated symphony that stimulates blood flow and promotes circulation throughout the body.

One of acupuncture’s most significant anti-aging benefits lies in its powerful anti-inflammatory effects. By reducing inflammation, acupuncture helps lower the risk of chronic diseases that speed up the aging process. It’s like an internal cleanup, where acupuncture helps your body fight against the invisible enemies of aging.

But the magic of acupuncture doesn’t stop there. This age-old therapy also serves as a stress-buster, managing stress levels effectively. High-stress levels can wreak havoc on our physical, mental, and emotional well-being, and unchecked fear, worry, and anxiety can lead to premature aging. Acupuncture helps to regulate the body’s stress response, promoting a sense of calm and well-being.

In essence, acupuncture is a gentle yet potent ally in our quest for graceful aging. It works on multiple fronts – enhancing circulation, reducing inflammation, and managing stress, contributing to a healthier, more youthful you.

Meditation

Scientific research reveals that meditation encourages healthy cell regeneration, reduces oxidative stress, and curtails inflammation in the body. It’s like giving your cells a rejuvenating spa treatment, helping them stay vibrant and youthful. Furthermore, meditation techniques such as mindfulness, deep breathing, and visualization have been found to reduce stress and anxiety, boost mood, and promote cognitive function. These techniques act as a mental workout for your brain, keeping it sharp and agile.

Meditation is not just about closing your eyes and sitting still; it’s a journey towards self-awareness and inner peace that brings about a sense of overall well-being. By incorporating meditation into your daily routine, you can tap into its powerful anti-aging benefits, fostering a healthier, more youthful you.

For more on how to start to meditate, Click Here

Stretching

Stretching, often overlooked in the quest for fitness, offers a wealth of benefits that can help slow down the aging process. The gentle pull and release of a good stretch can do wonders for your body, improving flexibility, increasing blood circulation, enhancing posture, promoting relaxation, and releasing muscle tension.

Flexibility is the first line of defense against the stiffness that often accompanies aging. Regular stretching exercises can help maintain or even improve your range of motion, making daily activities easier and more enjoyable. Moreover, stretching stimulates blood circulation, ensuring that your muscles, tissues, and organs receive adequate oxygen and nutrients. This improved circulation can speed up recovery from muscle soreness and enhance overall health.

Good posture isn’t just about aesthetics; it’s crucial for reducing strain on your muscles and joints. Stretching can help correct posture by lengthening tight muscles that pull parts of the body away from their intended position. Furthermore, stretching exercises have a calming effect on the mind, promoting relaxation and helping to release muscle tension.

Incorporating stretching into your daily routine doesn’t require a lot of time or special equipment. Try simple moves like the forward bend to stretch your hamstrings, the chest stretch to open up your chest and shoulders, or the cat-camel stretch for a gentle spine massage. Remember to breathe deeply and relax into each stretch for maximum benefit.

For more on stretching Click Here

Potential Side Effects

While these strategies may have potential benefits, it’s important to be aware of potential side effects. For instance, while some supplements are generally safe for most people, others can interact with medications or have side effects. Always consult with a healthcare provider before starting any new supplement regimen.

Conclusion

Aging is a complex process influenced by numerous factors. While we can’t stop aging entirely, research suggests that certain strategies may help slow down the process. By understanding the science behind aging, we can make informed decisions about our health and lifestyle.

Remember, a healthy diet, regular exercise, adequate sleep, and stress management are all crucial elements of a comprehensive anti-aging strategy. And always consult with a healthcare professional before beginning any new supplement regimen or treatment.


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13/Dec/2022

Vitamin D is an essential vitamin that helps our body absorb calcium, promote healthy bones and teeth, and regulate our immune system. It’s often referred to as the “sunshine vitamin” because our body creates it when we’re exposed to sunlight. But many people have difficulty getting enough vitamin D from exposure to the sun alone, especially in winter. Therefore for some of us it is necessary to take a vitamin D supplement to achieve optimal levels.
So what are the main benefits of vitamin D? Let’s take a look at 10 top benefits of this important nutrient.

1. Strengthens Bones and Teeth

Vitamin D plays a pivotal role in helping our bodies absorb calcium, which is essential for strong bones and teeth. Research has shown that having low levels of vitamin D can increase your risk of developing osteoporosis, a condition characterized by weak and brittle bones, in later life.

2. Improves Immunity

Studies have found that people with adequate levels of vitamin D are better able to fight off infections such as colds and flu than those who don’t get enough of the nutrient in their diets. This is because Vitamin D helps regulate our immune system by producing proteins called antimicrobial peptides that help fight off invading bacteria and viruses.

3. Helps Regulate Blood Pressure

Low levels of vitamin D can lead to higher blood pressure, which can increase your risk for heart disease and stroke if left unchecked over time. Adequate levels of vitamin D help keep your blood pressure at healthy levels, reducing your overall risk for cardiovascular-related health issues.

4. Reduces Inflammation

Inflammation is one of the body’s natural processes which helps protect us from infection and injury, but too much inflammation can be damaging to our health over time. Low levels of vitamin D have been linked to increased inflammation in the body, so maintaining optimal amounts through diet or supplementation may help reduce the risk for chronic inflammatory diseases such as asthma or arthritis.

5. Improves Mental Health

Recent studies have shown that there may be a link between low levels of vitamin D and depression or anxiety symptoms in some individuals. It’s believed that this connection may be due to how vitamin D affects certain neurotransmitters in the brain such as serotonin which play a role in regulating mood and emotions.

6. Protects Against Cancer

Low levels of vitamin D have been associated with an increased risk for certain types of cancer including colon cancer, breast cancer, prostate cancer, and ovarian cancer among others. While more research needs to be done on this topic, it’s believed that adequate intake or exposure to sunlight could help reduce your overall risk for developing these cancers over time.

7. Improves Muscle Strength

Vitamin D plays an important role in muscle strength since it helps regulate calcium absorption into muscles tissues which allows them to contract properly during exercise or physical activity. Research has also shown that having low levels of this vital nutrient could lead to weaker muscles over time so getting enough through diet or supplementation may help improve muscle strength over time.

8. Boosts Brain Function

Studies suggest that having adequate amounts of vitamin d could help boost cognitive function by improving memory recall and alertness. Vitamin D helps regulate certain neurotransmitters like glutamate which play a role in learning and memory formation.

9. Lowers Risk Of Diabetes

There is evidence suggesting that low levels of this nutrient could increase your chances for developing type 2 diabetes since it helps regulate insulin production.

10. Decreases Risk Of Heart Disease

Maintaining adequate amounts through diet or supplementation has been linked with lower risks for heart attack and stroke. Vitamin D helps reduce inflammation within arteries therefore decreasing plaque build-up overtime.

Vitamin D supplementation

Besides sun exposure, Vitamin D supplements provide the most convenient way to ensure the adequate dosage is taken; however it is recommended that you get a lab test done first to determine your Vitamin D levels and then adjust your supplementation accordingly. The current international recommendation for Vitamin D intake stands at 400-800 IUs/day, however some people may need higher doses depending on their individual situation. Vitamin D supplementation can also be obtained through dietary sources such as cod liver oil or fortified foods. When supplementation is not enough to raise a severely low vitamin D level, a high dose injection is an option. For more information on how sun exposure affects vitamin D click here.

Conclusion

As you can see, there are numerous benefits associated with getting enough Vitamin D through diet or exposure to sunlight everyday! From strengthening bones and teeth, to reducing inflammation and improving mental health —this essential nutrient truly plays an integral role in keeping us healthy! For those who aren’t able to get enough naturally through foods rich in Vitamin D like fatty fish (such as salmon), eggs, mushrooms, and fortified milk, supplementation may be necessary depending on individual needs. Consulting with a medical professional would be a great way to ensure that your vitamin D level is optimal.

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22/Sep/2018

Cold and Flu season is here! Now that kids are back to school and the season is changing we should start thinking about preventing colds and flu. As a Naturopathic Doctor part of my job is counseling parents on safe and effective ways to treat and prevent colds and flu for the whole family. Here are 5 things that will help prevent colds and flu and can even help to ameliorate symptoms and shorten duration of an active infection.

 

Probiotics

  1. Probiotics

Probiotics help boost the immune system – Studies have shown that probiotics affect immune cells throughout the body. When certain strains of probiotics are introduced into our intestine they help to repair intestinal cells and they boost production of antimicrobial substances. In one study, 326 children aged 3-5 years were randomly assigned to receive, in double-blind fashion, probiotic supplementation. Treatments were given twice per day in divided doses for 6 months, including the winter season. Compared with placebo, the probiotic group had the following results; fever reduction 53-73%, cough reduction 41-62%, decreased runny nose 28-59%, decreased need for antibiotics 68-82%, reduced absence from school 28-32%.

Elderberry

  1. Elderberry

Elderberry extracts inhibit bacteria and viruses – Not only does elderberry syrup taste great, studies have shown that it inhibits the bacteria and viruses associated with common colds and the flu. One study demonstrated that an elderberry liquid extract possesses antimicrobial activity against both streptococci bacteria and influenza viruses. Another study looked at 312 air travellers flying from Australia to an overseas destination.  Those travellers who took an elderberry extract before, during and after travel had fewer colds, less sick days and less symptoms.

Vitamin C

  1. Vitamin C

Vitamin C supports immune cells – Vitamin C is very important for optimal immune system functioning. Vitamin C helps immune cells get to where they need to be, kill pathogens effectively, protect the body from damage and clean up after battling infections. Studies have shown that adequate vitamin C in the blood helps prevent infections, is necessary to fight infections and helps with recovery. The recommended daily intake of vitamin C is 100-200mg/day; however during active infection, the metabolic demand increases and therefore the requirement for vitamin C is likely to be higher. Even in this day and age, vitamin C is the fourth leading nutrient deficiency in North America. Poor diet and increases in free radical exposure due to an unhealthy lifestyle may be contributing factors. Excellent sources of vitamin C are Broccoli, Citrus Fruits and Berries.

Zinc

  1. Zinc

Zinc is essential for immune system communication – The importance of zinc for proper immune function has been well established. Zinc deficiency undoubtedly causes immune system malfunction.  The cells of our body are in constant communication. During infection there is a need for effective communication between immune cells in order to get rid of the “bad guys”.  Communication happens in the form of chemical messengers and enzymes. Zinc is an essential component of these chemicals and enzymes. As with vitamin C, during active infection our requirement for zinc is likely to increase. Studies have shown that Zinc supplementation during infection can shorten the duration of the illness. Excellent dietary sources of zinc include: Meat, Shellfish, Legumes, Nuts and Seeds. Supplementation may be important with a vegan or vegetarian diet.

Vitamin D from Sunlight

  1. Vitamin D

Vitamin D is the supervisor of the immune system –Vitamin D has many functions in the body, and receptors for vitamin D can be found on many different tissues. One important function for vitamin D is in the modulation of our immune system. Studies have suggested that vitamin D is able to both calm down and rev-up the immune system according to what our body needs it to do. This is why Vitamin D is thought to be as important in autoimmune disorders as it is in infections.

Vitamin D deficiency can cause the immune system to behave erratically. Unfortunately in Canada we have one of the highest incidences of vitamin D deficiency in the world. Our primary source of vitamin D is from sunlight and therefore supplementation becomes important especially during the winter months. Studies have shown that there is a higher incidence of upper respiratory tract infections in athletes who are deficient in the vitamin and who train in the wintertime. Supplementation had preventative and symptom reducing effects. Aside from sunlight, some dietary sources of vitamin D are: fortified foods, fatty fish, beef liver, egg yolks and cheese.

 

Even vitamins and minerals at high dosages can be dangerous, especially in children. It is always recommended to consult with a health care professional, such as a Naturopathic Doctor, before supplementing on your own.

 

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Leyer, GJ et al. Probiotic effects on cold and influenza-like symptom incidence and duration in children. Pediatrics 2009; 124-179. Walker, WA. Mechanisms of action of probiotics. Clin Infect Dis. 2008; 46 (Suppl2): S87-91.

Curr Opin Gastroenterol. 2011 October ; 27(6): 496–501. doi:10.1097/MOG.0b013e32834baa4d.  Probiotics and immune health Fang Yana and D.B. Polkb,c,d

Elderberry Supplementation Reduces Cold Duration

and Symptoms in Air-Travellers: A Randomized,

Double-Blind Placebo-Controlled Clinical Trial Evelin Tiralongo 1,2, *, Shirley S. Wee 2,3 and Rodney A. Lea 4 Received: 8 February 2016; Accepted: 18 March 2016; Published: 24 March 2016

 

Krawitz et al. BMC Complementary and Alternative Medicine 2011, 11:16

http://www.biomedcentral.com/1472-6882/11/16

Inhibitory activity of a standardized elderberry

liquid extract against clinically-relevant human

respiratory bacterial pathogens and influenza A

and B viruses Christian Krawitz1†, Mobarak Abu Mraheil1†, Michael Stein2, Can Imirzalioglu1, Eugen Domann1, Stephan Pleschka2*,

Torsten Hain1*

 

Vitamin C and Immune Function Anitra C. Carr 1, * and Silvia Maggini 2

1 Department of Pathology, University of Otago, Christchurch, P.O. Box 4345, Christchurch 8140, New Zealand

2 Bayer Consumer Care Ltd., Peter-Merian-Strasse 84, 4002 Basel, Switzerland; silvia.maggini@bayer.com* Correspondence: anitra.carr@otago.ac.nz; Tel.: +643-364-0649 Received: 21 September 2017; Accepted: 31 October 2017; Published: 3 November 2017

 

Biofactors. 2014 Jan-Feb;40(1):27-40. doi: 10.1002/biof.1114. Epub 2013 Jun 27.Zinc signals and immune function. Haase H1Rink L.

 

Cochrane Database Syst Rev. 2013 Jun 18;(6):CD001364. doi: 10.1002/14651858.CD001364.pub4. Zinc for the common cold.

Singh M1Das RR.

 

Vitamin D3 Supplementation Reduces the Symptoms

of Upper Respiratory Tract Infection during Winter

Training in Vitamin D-Insufficient Taekwondo

Athletes: A Randomized Controlled Trial Hyun Chul Jung 1 , Myong-Won Seo 2  , Sukho Lee 3 , Sung Woo Kim 2  and Jong Kook Song 2, * 1 Department of Kinesiology, College of Health Sciences, University of Louisiana at Monroe, 700 University

Avenue, Monroe, LA 71209, USA; jung@ulm.edu

2 Department of Taekwondo, College of Physical Education, Kyung Hee University, 1732 Deokyoungdaero, Giheung-gu, Yongin-si, Gyeonggi-do 17014, Korea; smilly1004@khu.ac.kr (M.-W.S.); kswrha@khu.ac.kr (S.W.K.)

3 Department of Counseling, Health, and Kinesiology, College of Education and Human Development,Texas A&M University-San Antonio, One University Way, San Antonio, TX 78224, USA; slee@tamusa.edu* Correspondence: jksong@khu.ac.kr; Tel.: +82-31-201-2708 Received: 2 August 2018; Accepted: 10 September 2018; Published: 14 September 2018

 

Mechanisms Underlying the Regulation of Innate and

Adaptive Immunity by Vitamin D Ran Wei and Sylvia Christakos *

Received: 25 June 2015 ; Accepted: 15 September 2015 ; Published: 24 September 2015 Department of Microbiology, Biochemistry and Molecular Genetics, New Jersey Medical School, Rutgers, the State University of New Jersey, 185 South Orange Ave, Newark, NJ 07103, USA; weira@njms.rutgers.edu

* Correspondence: christak@njms.rutgers.edu; Tel.: +973-972-4033; Fax: +973-972-5594


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31/Aug/2018

Multiple Sclerosis is a complex disease; those living with it need a simple approach. A treatment approach should appreciate the physiology of the disease process without neglecting the human body as a holistic system, and the patient as a person.

Naturopathy is an ideal philosophy of medicine for the treatment of M.S. as it aims to address disease processes and symptoms without loosing sight of the patient as an individual.

I chose to focus in neurological disease early into my professional career and as a result I have come across many complex chronic diseases of the nervous system including all subtypes of M.S. When patients come for their initial visit it is not uncommon to be privy to a long list of life events that have impacted the disease, symptoms that have evolved over years and medications that have been tried, stopped and tried again.

It’s easy to see why the practitioner on the other end of the patient with M.S. can become overwhelmed and confused, loosing sight of the big picture, dismissing the patients needs and goals. Unfortunately, this medical tunnel vision re-aimed at addressing each and every concern translates into complex and confusing treatment plans that most patients cannot comply with. I sympathize with these patients who have to remember to take dozens of pills while also dealing with a life altering condition.

To make matters worse, these confusing treatment plans hardly ever work because they tend to forget that the human body is not a series of islands, rather it’s a society striving to work in harmony and balance. The key to developing a simple, understandable and effective treatment plan is to figure out what is out of balance and how do we bring it back.

A typical treatment plan for M.S. has three parts: Foundations, The Immune System and Specific Symptoms. Since we are working toward bringing the body back into balance it is important to take the time to hear the full story and timeline of how the condition started and progressed. Often during the initial consultation it will become clear as to what type of events precluded the first attack and how these events triggered a physiological imbalance.

Diet therapy in multiple sclerosis

Foundations

It’s a futile effort to try and treat symptoms while the very basics of health and wellness are not fortified. The foundations of health can be summed up into three parts: Sleep, Diet and Exercise.

Sleep is the healing chamber for the body. Recently studies have shown that the brain undergoes a type of detoxification process while we sleep. Many neurodegenerative diseases have been correlated to poor sleeping habits. It is common to see sleeping issues in patients with M.S. In fact I have had a few cases where years of terrible sleep may have contributed to the patient experiencing their first symptoms related to M.S. This makes sense in the light of the new research demonstrating how important sleep is in clearing neurotoxic compounds from the brain.

One of the most important protocols I put together for my M.S. patients is aimed at improving sleep. This is achieved through sleep hygiene education and supplements that have been carefully vetted over my years in practices for their effectiveness in improving sleep initiation and maintenance.

Diet is important for a number of reasons, some are general and some are specific to M.S. The food we eat and its relation to our digestive tract determines our nutritional robustness.

M.S. is a chronic neuro-inflammatory state and therefore patients with M.S. will be using up vitamins and minerals involved in inflammatory processes at a greater rate than in a healthy control group. Therefor it’s important to determine what the nutritional status is of the M.S. patient (through consultation and specific lab tests), bring it back into balance and correct deficiencies. Otherwise the body will be unable to cope with the inflammatory process and the disease will progress.

It is also important to identify any food allergens, intolerances and sensitivities in the M.S. patient for these will perpetuate the inflammation. Chronic inflammation has a detrimental effect on the immune system, which I will discuss further in the next part of the treatment plan.

Another aspect related to diet is the health of the gastrointestinal tract and more specifically the micro-biome (the bacteria of the gut). A healthy micro-biome is important for detoxification, nutrient absorption and immune system regulation. A protocol addressing diet will focus on testing for nutritional deficiencies, food sensitivities, specific dietary guidelines for M.S. and supportive supplements where necessary.

A good dietary resource specific to M.S. is The Wahls Protocol.

physiotherapy for Multiple SclerosisExercise is a powerful health modulator and is under-appreciated for its importance in chronic disease and specifically M.S. Often exercise comes in the form of physiotherapy in progressive M.S. and the first thing I will do with a patient is set them up with one of the physiotherapists in my clinic (if they don’t already have a physiotherapy program). Often patients newly diagnosed with M.S. are neglected by the medical system in terms of exercise. In-patient rehab programs are inadequate, scooters and wheelchairs are promoted over therapy. Exercise and physiotherapy are instrumental in promoting neuroplasticity, decreasing inflammation, improving energy metabolism, maintaining and improving upon range of motion.

My clinic specializes in neurological rehabilitation using the Bobath Physiotherapy approach. Physio-Logic

The Immune System

Multiple Sclerosis is an autoimmune condition and therefore one cannot overlook the role of the immune system. Autoimmunity basically translates to a confused immune system that has targeted healthy cells and tissues rather than disease. The philosophy behind this part of the treatment plan addresses two questions: how the immune system became confused and how to bring it back into harmony.

There are many theories as to the cause of M.S., to name a few: Genetics, Vitamin D deficiency, Environmental Toxin Exposure, Candida Overgrowth, Dairy Protein Antigen Confusion and Leaky Gut Syndrome. There are truths to be told within many of these theories but in reality we just don’t know exactly what causes M.S. Some things we do know are the triggers for symptom activation, and things that reduce the risk of developing M.S. We know that stress (physical and/or emotional) often precipitate symptom relapse and progression. We also know that having adequate vitamin D levels are protective toward the development of M.S.

Vitamin D from SunlightVitamin D is not longer thought of as merely a bone-building vitamin. In reality it is more of a hormone and has a very important role in maintaining the health of the immune system. Step one of addressing the immune system is making sure the patient has optimal levels of vitamin D and if not, to adjust those levels using specific supplemental doses of vitamin D along with calcium and regular follow-up blood work.

Stress, whether it physical or emotional, causes a burden on the body. Most of the time we are able to cope with short durations of stress; however, when the stressful event is severe enough or lasts long enough it can impact the immune system in a negative way. Chronic stress can affect the immune system in two ways: Creating chronic inflammation that harms tissues and suppressing immune cells needed to fight infection.

When the immune system is under prolonged stress it becomes tired and makes mistakes, much like how we feel when under stress. One of these possible mistakes is mounting an autoimmune attack, harming normal healthy tissue rather than disease. Prolonged stress also depletes natural anti-inflammatory compounds like cortisol, allowing inflammation to run amuck. Therefore the protocol built around the immune system is aimed at decreasing stress on the immune system and bringing the immune system back into balance.

Anything that can be causing unnecessary inflammation needs to be dealt with and therefore chronic infections and food sensitivities must be addressed. Specific lab testing is used to investigate infections and sensitivities. Common food sensitivities in M.S. patients include: Dairy, Gluten, Yeast and Egg.

Once the major obstacles to a healthy immune system are removed we can work toward assisting the immune system back into a balanced state. The most important cells involved in bringing the immune system back into balance are “regulatory T cells” also known as “T suppressor cells”. These cells maintain tolerance in the immune system preventing autoimmunity. Part of the protocol is therefore aimed at supporting these cells. Some compounds that influence regulatory T cells are: probiotics, vitamin D, vitamin A, Omega 3 fatty acids and food sensitivities.

Sleep

Specific Symptoms

Treating foundations and immune system irregularities take time, therefore it is almost equally important to address the specific symptoms of the patient. Fatigue, weakness and pain are often obstacles to important foundational concerns like sleep and exercise.

Fortunately, there are many great strategies within Naturopathic medicine to help address the most common symptoms in M.S. namely: Weakness, Spasticity, Fatigue, Pain, Bowel and Bladder issues. There are dozens of supplements that have shown promise in treating the common symptoms of M.S. The art of the practitioner is in choosing the right compounds for the right patient. As an example, medical marijuana can be very effective for spasticity, pain, bladder dysfunction and sleep but can exacerbate weakness. A good practitioner with experience in treating M.S. will know how to choose the appropriate medications for the patients needs.

Multiple Sclerosis is a complex condition with many subtypes and many different ways it affects the individual patient. Naturopathic medicine aims to treat the root cause of disease while also addressing the individual concerns of the patient. The treatment plan can be summed up into three areas: Foundations, Immune System and Specific Symptoms. This helps direct the practitioner toward the right approach and simplifies the philosophy behind the treatment, improving upon compliance and therefore patient outcomes.

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18/Apr/2018

A Naturopathic Doctor can play an important role in managing CMT through dietary counseling, specialized testing and by offering relevant integrative therapies.

CMT is a hereditary disorder affecting the motor and sensory nerves.  It’s characterized by progressive loss of muscle tissue and sensation in various parts of the body. Currently CMT is incurable and is the most common inherited neurological disorder and affects approximately 1 in 2,500 people.

In terms of managing CMT, by far the most important goal is to maintain movement, muscle strength and flexibility. Often overlooked is the role diet, pain management and antispasmodics can play in CMT. Having a naturopathic doctor familiar with neurological conditions can be a valuable part of a healthcare team.

 

Sugar

Although sugar is sweet and delicious, at high concentrations it can become a poison for the nervous system. Uncontrolled blood sugar, including diabetes, will exacerbate nerve damage and peripheral neuropathy in CMT. A naturopathic doctor can test blood sugar in order to determine if it poses a risk. Dietary counseling, such as education around glycemic index and glycemic load, can help balance blood sugar levels. There are also effective strategies that can boost insulin sensitivity thus lowering blood sugar. These include; low impact exercise and supplements like chromium, berberine, agaricus mushroom, american ginseng, and vitamin B3.

 

Diet

A diet rich in antioxidants and anti-inflammatory compounds can greatly improve neuromotor and locomotor performance. Curcumin and vitamin C are two natural compounds that have been and are currently being investigated as potential therapeutic agents for CMT. One study demonstrated a decrease in neuron death and an increase in size and number of nerve sheath cells after administration of curcumin. Intermittent fasting is a diet strategy that promotes a 16 hour fasting period each day and has been shown to improve locomotor functioning in CMT patients after 5-months.

 

Nerve Pain

Nerve pain and neuropathy can be addressed through a few different approaches. Application of topical counterirritants such as capsaicin and menthol can work by overriding pain signals. Peripheral pain blockers work by re-routing pain signals locally at the source of the pain. Effective peripheral pain blockers include: acupuncture, electro-acupuncture, moxabustion and transcutaneous electrical nerve stimulation (TENS).  Central pain blockers block or override pain signals where they are interpreted, in the brain. Central pain blockers include cannabis, wild lettuce and california poppy.

 

Cramps and Spasms

There are many effective integrative therapies for cramps and muscle spasms. These therapies work by balancing electrical conduction at the muscle and stimulating inhibitory neurotransmitters. Some of the most effective therapies are: magnesium, acupuncture, GABA, valerian, cramp bark, skullcap, passionflower and cannabis.

 

Nerve-Protection

One of the largest areas a naturopathic doctor can serve as a crucial part of the integrative healthcare team is in offering strategies to prevent further nerve damage, and in some cases reversing existing nerve damage. Neuroprotectants generally belong to two main categories: antioxidants and anti-inflammatories. Neuroprotectant antioxidants include: alpha lipoic acid, glutathione, resveratrol, EGCG, flavonoids, Co-Q10, CBD and THC. Anti-inflammatory strategies include testing for food sensitivities, hormone levels and environmental toxins.  Anti-inflammatory supplements include Omega 3 fatty acids, curcumin, boswelia, and CBD.


Shawn-I.V..jpg
13/Oct/2015

Title: Reduction in symptoms associated with Fibromyalgia at six weeks using Intravenous Vitamins and Minerals (Myers Cocktail).

Running Header: Myers Cocktail for Fibromyalgia

Author: Dr. Shawn Meirovici N.D.

Physio-Logic 96 Scarsedale Road, Toronto, Ontario, M3B 2R7

Disclaimer: Patient consent was obtained

Key words: Intravenous, Vitamins, Minerals, Fibromyalgia

Abstract: Fibromyalgia is a musculoskeletal disorder characterized by widespread pain commonly with one or more coexisting symptoms. Treatment often includes both non-pharmacological and pharmacological therapy. Pharmacological therapy includes the use of antidepressants and GABA derivatives with varying success rates and often with unpleasant side effects. Micronutrient infusion is a newer approach with the majority of use in the field of alternative medicine. To date one placebo controlled pilot study has examined its use in fibromyalgia patients noting statistically significant effects on pain and fatigue. The following is a case study using a similar “cocktail” as the one used in the placebo controlled trial, for 4 treatments using the modified visual analogue scale of the fibromyalgia impact questionnaire (mVASFIQ) as an endpoint measure. Significant reduction in all parameters of the mVASFIQ was noted at 6 weeks, suggesting that micronutrient infusion should be further investigated as a treatment approach for fibromyalgia.

 

Background: I have a special interest in the treatment of chronic pain. Operating out of a rehabilitation clinic in Toronto, Canada has allowed me the opportunity to work with neurological conditions and traumatic injuries of which chronic pain is often a prevalent symptom. Fibromyalgia is characterized by chronic widespread pain and often involves disruption of many body systems including the gastrointestinal tract. While pharmaceutical intervention is focused on regulating the body’s response to pain, many alternative therapies are focused on restoring function to debilitated body systems. One such treatment is the Myers Cocktail: a intravenous micronutrient therapy that delivers vitamins and minerals directly into the blood stream thereby  bypassing the gastrointestinal tract. There is both a review and placebo controlled pilot study demonstrating intravenous micronutrient therapy as an effective treatment for symptom reduction in fibromyalgia. [1] [2]

 

Introduction: Fibromyalgia is characterized by chronic widespread pain, increased tenderness at specific sites known as “tender points,” un-refreshing sleep, fatigue and cognitive dysfunction not attributable to other disease states. While the etiology of fibromyalgia is not entirely clear, associations with trauma, adverse life events, impaired mood, anxiety, irritable bowel syndrome, cold intolerance, paresthesias and other medical conditions have been described. The pharmacologic treatment of fibromyalgia ranges from antidepressants to analgesics. Here we are commenting on a novel treatment involving the infusion of vitamins and minerals also known as a Myers Cocktail.

 

Case Presentation: J.M. is a 38-year old female who had been diagnosed with fibromyalgia in 2008. Her  symptoms started approximately 10 years ago after enduring a series of traumatic life events. Symptoms included: chronic widespread pain, non-restorative sleep, muscle weakness, morning stiffness, subjective swelling, multiple chemical sensitivities, frequent severe headaches, vestibular dysfunction, TMJ, paresthesia, chronic fatigue, dysmenorrhea, anxiety and irritable bowel syndrome. J.M. had tried a number of GABA derivatives, antidepressants and analgesics with varying degrees of relief but with significant adverse reactions including aphasia, depression and dyspepsia. At initial presentation, J.M. was taking Wellbutrin 300mg XL daily and Tylenol with Codeine as needed. She felt that she was starting to develop a tolerance to Wellbutrin. She was not taking any dietary supplements and was not on any type of specialized diet or exercise program.

J.M. was prescribed an intravenous infusion Myers Cocktail (B-complex 1ml, Dexpanthenol 250mg, Pyridoxine 100mg, Hydroxocobalamin 1mg, Ascorbic Acid 2000mg, Calcium Chlroide 100mg, Magnesium Chloride 1000mg and Sterile Water 46ml) via 60cc syringe with a 24 Gauge butterfly needle at the right median cubital vein, delivered over 15 minutes once per week for 4 infusion sessions. This patient completed a modified visual analogue scale of the fibromyalgia impact questionnaire (mVASFIQ) at initial consult (Image 1) and again after her final infusion (Image 2). She was also prescribed magnesium malate 1.5 grams per day, 1000iu vitamin D per day and 1mg melatonin at night 30 minutes before sleep. However, J.M. was admittedly not taking these supplements consistently during the 4 weeks of intravenous treatment.

The mVASFIQ score at treatment initiation was: (Fatigue 9.5, Insomnia 9.5, Depression 4.5, Anxiety 6.5, Rigidity 8.5, Pain 8.5, Difficulty with work 8.5) at four weeks the mVASFIQ score was: (Fatigue 3, Insomnia 5, Depression 1, Anxiety 3, Rigidity 3, Pain 3, Difficulty with work 3). Besides mild nausea and flushing during the first treatment no adverse effects were reported.

 

Discussion: Micronutrient infusion delivers vitamins and minerals involved in stress response, muscle contraction and nerve signaling, while able to bypass the need for gastrointestinal absorption. This is an effective delivery method for chronic conditions, such as fibromyalgia, where there is often gastrointestinal disruption as well as the potential for micronutrient deficiencies. The results of this case study demonstrate that micronutrient infusion Myers Cocktail may be an effective treatment for fibromyalgia related symptoms as indicated by a  decreased in symptoms score on mVASFIQ at 6 weeks post treatment. This joins the small collection of evidence for the validity of this treatment for fibromyalgia. More study into this treatment for fibromyalgia is warranted.

 

Confounding Factors: As was outlined in the treatment plan, J.M. received a few dietary supplements on initial consult; however, J.M. admitted to not taking these consistently throughout the 4 intravenous treatments. The patient received all 4 infusions by myself and was not blinded to the treatment. There was also no placebo control. Additionally, the patient may have been influenced by the doctor patient relationship or through placebo effect. However the significant improvement observed within a relatively short time helps to validate the results of this study.

[1] Intravenous Micronutrient Therapy (Myers’ Cocktail) for Fibromyalgia: A Placebo-Controlled Pilot Study, Ather et al., The Journal of Alternative and Complementary Medicine, Volume 15, Number 3, 2009, pp. 247-257

[2] Myers’ Cocktail, Dr. Alan Gaby M.D., Alternative Medicine Review, Volume 7, Number 5, 2002.

 Image 1

Table 1

mVASFIQ for J.M. on July 18th 2015 (patient incorrectly marked X in box rather than a check through the appropriate line, therefore, results have +/- 0.5 confidence interval.

Image 2

Table 2

mVASFIQ for J.M August 28th 2015.


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